Diet, lifestyle and genetic susceptibility

Every day, each Dane consumes an average of 3 kilograms of food and fluids, which amounts to a ton each year. Food consumption habits have both health and environmental consequences. In the research group, we study associations between diet, lifestyle and health. The main outcomes we focus on are obesity, cardiovascular disease and cancer, both in one generation and across generations in families. Increasingly, we also study the interplay between food consumption, environmental impact, and health.

Research areas

  • Applying novel methods to assess associations between diet and health
  • Modelled substitution of foods
  • Socioeconomic determinants of food and drink habits
  • Associations between diet, lifestyle and obesity exposures in one generation, and health outcomes in the next
  • Environmentally sustainable foods or dietary habits and health
  • The interplay between genetic variation, diet, and health

Recent publications

Publications

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Tsilidis, K. K., Allen, N. E., Key, T. J., Sanjoaquin, M. A., Bakken, K., Berrino, F., Fournier, A., Lund, E., Overvad, K., Olsen, A., Tjønneland, A., Byrnes, G., Chajes, V., Rinaldi, S., Boutron-Ruault, M.-C., Clavel-Chapelon, F., Chang-Claude, J., Kaaks, R., Bergmann, M. ... Riboli, E. (2011). Menopausal hormone therapy and risk of colorectal cancer in the European prospective investigation into cancer and nutrition. International Journal of Cancer, 128(8), 1881-1889. https://doi.org/10.1002/ijc.25504
Tsilidis, K. K., Allen, N. E., Key, T. J., Bakken, K., Lund, E., Berrino, F., Fournier, A., Olsen, A., Tjønneland, A., Overvad, K., Boutron-Ruault, M.-C., Clavel-Chapelon, F., Byrnes, G., Chajes, V., Rinaldi, S., Chang-Claude, J., Kaaks, R., Bergmann, M., Boeing, H. ... Riboli, E. (2010). Oral contraceptives, reproductive history and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition. British Journal of Cancer, 103(11), 1755-1759. https://doi.org/10.1038/sj.bjc.6605965
Tsilidis, K. K., Allen, N. E., Key, T. J., Dossus, L., Kaaks, R., Bakken, K., Lund, E., Fournier, A., Dahm, C. C., Overvad, K., Hansen, L., Tjønneland, A., Rinaldi, S., Romieu, I., Boutron-Ruault, M.-C., Clavel-Chapelon, F., Lukanova, A., Boeing, H., Schütze, M. ... Riboli, E. (2011). Menopausal hormone therapy and risk of ovarian cancer in the European prospective investigation into cancer and nutrition. Cancer Causes & Control, 22(8), 1075-84. https://doi.org/10.1007/s10552-011-9782-z
Tsilidis, K. K., Allen, N. E., Appleby, P. N., Rohrmann, S., Nöthlings, U., Arriola, L., Gunter, M. J., Chajes, V., Rinaldi, S., Romieu, I., Murphy, N., Riboli, E., Tzoulaki, I., Kaaks, R., Lukanova, A., Boeing, H., Pischon, T., Dahm, C. C., Overvad, K. ... Key, T. J. (2015). Diabetes mellitus and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition. International Journal of Cancer, 136(2), 372-81. https://doi.org/10.1002/ijc.28989
Tschiderer, L., Peters, S. A. E., van der Schouw, Y. T., van Westing, A. C., Tong, T. Y. N., Willeit, P., Seekircher, L., Moreno-Iribas, C., Huerta, J. M., Crous-Bou, M., Söderholm, M., Schulze, M. B., Johansson, C., Själander, S., Heath, A. K., Macciotta, A., Dahm, C. C., Ibsen, D. B., Pala, V. ... Onland-Moret, N. C. (2023). Age at Menopause and the Risk of Stroke: Observational and Mendelian Randomization Analysis in 204 244 Postmenopausal Women. Journal of the American Heart Association, 12(18), Article e030280. https://doi.org/10.1161/JAHA.123.030280
Tschiderer, L., Peters, S. A. E., van der Schouw, Y. T., Burgess, S., Luijken, J., Bijmolt, C., Soliman, H., Butterworth, A. S., Wood, A. M., Tong, T. Y. N., Dahm, C. C., Seekircher, L., Tjønneland, A., Mellemkjær, L., Schulze, M. B., Masala, G., Sieri, S., Panico, S., Sacerdote, C. ... Onland-Moret, N. C. (2025). Reassessing the association between age at menarche and cardiovascular disease: observational and Mendelian randomization analyses. European Journal of Preventive Cardiology, 32(10), 857–866. https://doi.org/10.1093/eurjpc/zwaf051
Trichopoulou, A., Orfanos, P., Norat, T., Bueno-De-Mesquita, HB., Ocke, MC., Peeters, PH., van der Schouw, YT., Boeing, H., Hoffmann, K., Bofetta, B., Nagel, G., Masala, G., Krogh, V., Panico, S., Tumino, R., Vineis, P., Bamia, C., Naska, A., Benetou, V. ... Trichopoulos, D. (2005). Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study. BMJ, 330, 991-7.

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