Diet, lifestyle and genetic susceptibility

Every day, each Dane consumes an average of 3 kilograms of food and fluids, which amounts to a ton each year. Food consumption habits have both health and environmental consequences. In the research group, we study associations between diet, lifestyle and health. The main outcomes we focus on are obesity, cardiovascular disease and cancer, both in one generation and across generations in families. Increasingly, we also study the interplay between food consumption, environmental impact, and health.

Research areas

  • Applying novel methods to assess associations between diet and health
  • Modelled substitution of foods
  • Socioeconomic determinants of food and drink habits
  • Associations between diet, lifestyle and obesity exposures in one generation, and health outcomes in the next
  • Environmentally sustainable foods or dietary habits and health
  • The interplay between genetic variation, diet, and health

Recent publications

Publications

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Manfredi, L., Buscema, F., Giraudo, M. T., Sodano, B., Padroni, L., Destefanis, C., Freisling, H., Ferrari, P., Cesaroni, G., Uzzau, S., Schulze, M. B., Saieva, C., Tumino, R., Weiderpass, E., Matta, K., Vaccarella, S., Guevara, M., Halkjær, J., Tjønneland, A. ... Ricceri, F. (2026). Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation into Cancer and Nutrition. Journal of Epidemiology and Community Health, 80(1), 3-9. Article jech-2025-224476. https://doi.org/10.1136/jech-2025-224476
Aguilera-Buenosvinos, I., Morales Berstein, F., González-Gil, E. M., Dossus, L., Gunter, M. J., Biessy, C., Masala, G., Santucci De Magistris, M., Laouali, N., Shah, S., Marques, C., Heath, A. K., Tsilidis, K. K., Cross, A. J., Ferrari, P., Castro-Espin, C., Debras, C., Tumino, R., Tjønneland, A. ... Toledo Atucha, E. (2025). Adherence to the Mediterranean Diet and Obesity-Linked Cancer Risk in EPIC. JAMA network open, 8(2), e2461031. Article e2461031. https://doi.org/10.1001/jamanetworkopen.2024.61031
Aglago, E. K., Ramos, I., Keski-Rahkonen, P., Chatziioannou, C., Freisling, H., Fedirko, V., Gunter, M. J., Dahm, C. C., Langmann, F., Bondonno, N., Tjønneland, A., Severi, G., Truong, T., Katzke, V., Kaaks, R., Bergmann, M., Schulze, M. B., Masala, G., Pala, V. ... Jenab, M. (2025). Alcohol and smoking habits in association with hepatocellular carcinoma risk. International Journal of Cancer, 157(4), 644-657. https://doi.org/10.1002/ijc.35401
Manfredi, L., Sodano, B., Raganato, C., Buscema, F., Milani, L., Catalano, A., Freisling, H., Ferrari, P., Abraha, A., Kaaks, R., Katzke, V., Panico, S., Antoniussen, C. S., Dahm, C. C., Tin, S. T., Vermeulen, R., Vaartjes, I., Tjønneland, A., Olsen, A. ... Ricceri, F. (2025). A longitudinal Analysis of the Association between Socioeconomic Position and Multimorbidity in the European Prospective Investigation into Cancer and Nutrition Study. Aging and Disease, 16(6), 3625-3637. https://doi.org/10.14336/AD.2024.1166

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