Diet, lifestyle and genetic susceptibility

Every day, each Dane consumes an average of 3 kilograms of food and fluids, which amounts to a ton each year. Food consumption habits have both health and environmental consequences. In the research group, we study associations between diet, lifestyle and health. The main outcomes we focus on are obesity, cardiovascular disease and cancer, both in one generation and across generations in families. Increasingly, we also study the interplay between food consumption, environmental impact, and health.

Research areas

  • Applying novel methods to assess associations between diet and health
  • Modelled substitution of foods
  • Socioeconomic determinants of food and drink habits
  • Associations between diet, lifestyle and obesity exposures in one generation, and health outcomes in the next
  • Environmentally sustainable foods or dietary habits and health
  • The interplay between genetic variation, diet, and health

Recent publications

Publications

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Jäger, S., Kuxhaus, O., Prada, M., Huybrechts, I., Tong, T. Y. N., Forouhi, N. G., Razquin, C., Corella, D., Martinez-Gonzalez, M. A., Dahm, C. C., Ibsen, D. B., Tjønneland, A., Halkjær, J., Marques, C., Cadeau, C., Ren, X., Katzke, V., Bendinelli, B., Agnoli, C. ... Schulze, M. B. (2025). Nut consumption, linoleic and α-linolenic acid intakes, and genetics: how fatty acid desaturase 1 impacts plasma fatty acids and type 2 diabetes risk in EPIC-InterAct and PREDIMED studies. BMC Medicine, 23(1), Article 344. https://doi.org/10.1186/s12916-025-04187-8
Andersen, J. L. M., Frederiksen, K., Kyrø, C., Hansen, J., Raaschou-Nielsen, O., Bork, C. S., Dahm, C. C., Tjønneland, A. & Olsen, A. (2025). Organic food consumption and the incidence of atherosclerotic cardiovascular disease in the Danish Diet, Cancer and Health cohort. European Journal of Preventive Cardiology, 32(16), 1575-1585. https://doi.org/10.1093/eurjpc/zwaf057
Dall, M., Herzog, K., Hufnagel, A., Ibsen, D. B., Lebiecka-Johansen, B., Ruppert, P. M. M., Preston, J. M., Toh, P. J. Y. & Yfanti, C. (2025). Our future, we decide: five ways to reform the scientific publication process. Nature Reviews Endocrinology, 21(1), 5-6. https://doi.org/10.1038/s41574-024-01056-x
Guo, P., Luo, J., Zhang, J., Bonde, J. P., Struciński, P., Ohniev, V., Arah, O. A., Deziel, N. C., Warren, J. L., Toft, G. & Liew, Z. (2025). Paternal and maternal exposures to per- and polyfluoroalkyl substances (PFAS) and birth outcomes: a multi-country cohort study. Environmental Health: A Global Access Science Source, 24, Article 48. https://doi.org/10.1186/s12940-025-01199-y
Grenville, Z. S., Noor, U., Rinaldi, S., Gunter, M. J., Ferrari, P., Agnoli, C., Amiano, P., Catalano, A., Chirlaque, M. D., Christakoudi, S., Guevara, M., Johansson, M., Kaaks, R., Katzke, V., Masala, G., Olsen, A., Papier, K., Sánchez, M.-J., Schulze, M. B. ... Travis, R. C. (2025). Perturbations in the blood metabolome up to a decade before prostate cancer diagnosis in 4387 matched case-control sets from the European Prospective Investigation into Cancer and Nutrition. International Journal of Cancer, 156(5), 943-952. https://doi.org/10.1002/ijc.35208
Córdova, R., Kim, J., Thompson, A. S., Noh, H., Shah, S., Dahm, C. C., Jensen, C. F., Mellemkjær, L., Tjønneland, A., Katzke, V., Le Cornet, C., El-Khoury, C., Schulze, M. B., Masala, G., Agnoli, C., Simeon, V., Tumino, R., Ricceri, F., Verschuren, W. M. M. ... Freisling, H. (2025). Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis. The Lancet Healthy Longevity, 6(8), Article 100742. https://doi.org/10.1016/j.lanhl.2025.100742

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