Diet, lifestyle and genetic susceptibility

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Every day, each Dane consumes an average of 3 kilograms of food and fluids, which amounts to a ton each year. Food consumption habits have both health and environmental consequences. In the research group, we study associations between diet, lifestyle and health. The main outcomes we focus on are obesity, cardiovascular disease and cancer, both in one generation and across generations in families. Increasingly, we also study the interplay between food consumption, environmental impact, and health.

Research areas

  • Applying novel methods to assess associations between diet and health
  • Modelled substitution of foods
  • Socioeconomic determinants of food and drink habits
  • Associations between diet, lifestyle and obesity exposures in one generation, and health outcomes in the next
  • Environmentally sustainable foods or dietary habits and health
  • The interplay between genetic variation, diet, and health

Recent publications

Publications

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Fedirko, V., Tran, H. Q., Gewirtz, A. T., Stepien, M., Trichopoulou, A., Aleksandrova, K., Olsen, A., Tjønneland, A., Overvad, K., Carbonnel, F., Boutron-Ruault, M.-C., Severi, G., Kühn, T., Kaaks, R., Boeing, H., Bamia, C., Lagiou, P., Grioni, S., Panico, S. ... Jenab, M. (2017). Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested case-control study. B M C Medicine, 15(1), 72. Article 72. https://doi.org/10.1186/s12916-017-0830-8
Romieu, I., Ferrari, P., Chajès, V., de Batlle, J., Biessy, C., Scoccianti, C., Dossus, L., Christine Boutron, M., Bastide, N., Overvad, K., Olsen, A., Tjønneland, A., Kaaks, R., Boeing, H., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Palli, D., Sieri, S. ... Riboli, E. (2017). Fiber intake modulates the association of alcohol intake with breast cancer. International Journal of Cancer, 140(2), 316-321. https://doi.org/10.1002/ijc.30415
Acar, E., Gürdeniz, G., Savorani, F., Hansen, L., Olsen, A., Tjønneland, A., Dragsted, L. O. & Bro, R. (2017). Forecasting Chronic Diseases Using Data Fusion. Journal of Proteome Research, 16(7), 2435-2444. https://doi.org/10.1021/acs.jproteome.7b00039
Perez-Cornago, A., Travis, R. C., Appleby, P. N., Tsilidis, K., Tjønneland, A., Olsen, A., Overvad, K., Katzke, V., Kühn, T., Trichopoulou, A., Peppa, E., Kritikou, M., Sieri, S., Palli, D., Sacerdote, C., Tumino, R., Bueno-De-Mesquita, B. H., Agudo, A., Larranaga, N. ... Key, T. J. (2017). Fruit and vegetable intake and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). International Journal of Cancer, 141(2), 287-297. https://doi.org/10.1002/ijc.30741
Nimptsch, K., Song, M., Aleksandrova, K., Katsoulis, M., Freisling, H., Jenab, M., Gunter, M. J., Tsilidis, K., Weiderpass, E., Bueno-de-Mesquita, H. B., Chong, D. Q., Jensen, M. K., Wu, C., Overvad, K., Kühn, T., Barrdahl, M., Melander, O., Jirström, K., Peeters, P. H. ... Pischon, T. (2017). Genetic variation in the ADIPOQ gene, adiponectin concentrations and risk of colorectal cancer: a Mendelian Randomization analysis using data from three large cohort studies. European Journal of Epidemiology, 32(5), 419-430. https://doi.org/10.1007/s10654-017-0262-y
Jakszyn, P., Fonseca-Nunes, A., Lujan-Barroso, L., Aranda, N., Tous, M., Arija, V., Cross, A. J., Bueno-de-Mesquita, HBA., Weiderpass, E., Kühn, T., Kaaks, R., Sjöberg, K., Ohlsson, B., Tumino, R., Palli, D., Ricceri, F., Fasanelli, F., Krogh, V., Mattiello, A. ... Agudo, A. (2017). Hepcidin levels and gastric cancer risk in the EPIC-EurGast study. International Journal of Cancer, 141(5), 945-951. https://doi.org/10.1002/ijc.30797
Huang, J., Zagai, U., Hallmans, G., Nyrén, O., Engstrand, L., Stolzenberg-Solomon, R., Duell, E. J., Overvad, K., Katzke, V. A., Kaaks, R., Jenab, M., Park, J. Y., Murillo, R., Trichopoulou, A., Lagiou, P., Bamia, C., Bradbury, K. E., Riboli, E., Aune, D. ... Ye, W. (2017). Helicobacter pylori infection, chronic corpus atrophic gastritis and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort: a nested case-control study. International Journal of Cancer, 140(8), 1727–1735. https://doi.org/10.1002/ijc.30590

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