Diet, lifestyle and genetic susceptibility
Every day, each Dane consumes an average of 3 kilograms of food and fluids, which amounts to a ton each year. Food consumption habits have both health and environmental consequences. In the research group, we study associations between diet, lifestyle and health. The main outcomes we focus on are obesity, cardiovascular disease and cancer, both in one generation and across generations in families. Increasingly, we also study the interplay between food consumption, environmental impact, and health.
Research areas
- Applying novel methods to assess associations between diet and health
- Modelled substitution of foods
- Socioeconomic determinants of food and drink habits
- Associations between diet, lifestyle and obesity exposures in one generation, and health outcomes in the next
- Environmentally sustainable foods or dietary habits and health
- The interplay between genetic variation, diet, and health
Recent publications
Publications
Ibsen, D. B., Levitan, E. B., Åkesson, A., Gigante, B. & Wolk, A. (2022). The DASH diet is associated with a lower risk of heart failure: a cohort study. European Journal of Preventive Cardiology, 29(7), 1114-1123. https://doi.org/10.1093/eurjpc/zwac003
Howe, L. J., Nivard, M. G., Morris, T. T., Hansen, A. F., Rasheed, H., Cho, Y., Chittoor, G., Ahlskog, R., Lind, P. A., Palviainen, T., van der Zee, M. D., Cheesman, R., Mangino, M., Wang, Y., Li, S., Klaric, L., Ratliff, S. M., Bielak, L. F., Nygaard, M. ... Within Family Consortium (Christina Dahm; member) (2022). Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects. Nature Genetics, 54(5), 581-592. https://doi.org/10.1038/s41588-022-01062-7
Clasen, J. L., Heath, A. K., Van Puyvelde, H., Huybrechts, I., Park, J. Y., Ferrari, P., Johansson, M., Scelo, G., Ulvik, A., Midttun, Ø., Ueland, P. M., Dahm, C. C., Halkjær, J., Olsen, A., Johnson, T., Katzke, V., Schulze, M. B., Masala, G., Segrado, F. ... Muller, D. C. (2021). A comparison of complementary measures of vitamin B6 status, function, and metabolism in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The American Journal of Clinical Nutrition, 114(1), 338-347. https://doi.org/10.1093/ajcn/nqab045
Zhang, J., Nyvang, D., Ibsen, D. B., Olsen, A., Tjønneland, A., Overvad, K. & Dahm, C. C. (2021). Adherence to the Danish food-based dietary guidelines and risk of colorectal cancer: a cohort study. British Journal of Cancer, 125(12), 1726-1733. https://doi.org/10.1038/s41416-021-01556-x
Markanti, L., Ibsen, D. B., Tjønneland, A., Overvad, K. & Dahm, C. C. (2021). Adherence to the Danish food-based dietary guidelines and risk of type 2 diabetes: the Danish diet, cancer, and health cohort. European Journal of Clinical Nutrition, 75(5), 836-844. https://doi.org/10.1038/s41430-020-00805-1
Dashti, S. G., English, D. R., Simpson, J. A., Karahalios, A., Moreno-Betancur, M., Biessy, C., Rinaldi, S., Ferrari, P., Tjonneland, A., Halkjær, J., Dahm, C. C., Vistisen, H. T., Menegaux, F., Perduca, V., Severi, G., Aleksandrova, K., Schulze, M. B., Masala, G., Sieri, S. ... Dossus, L. (2021). Adiposity and endometrial cancer risk in postmenopausal women: a sequential causal mediation analysis. Cancer Epidemiology, Biomarkers & Prevention, 30(1), 104-113. https://doi.org/10.1158/1055-9965.EPI-20-0965
Katzke, V., Le Cornet, C., Mahfouz, R., Brauer, B., Johnson, T., Canzian, F., Rebours, V., Boutron-Ruault, M.-C., Severi, G., Schulze, M. B., Olsen, A., Tjoenneland, A., Overvad, K., Crous-Bou, M., Molina-Montes, E., Amiano, P., Huerta, J. M., Ardanaz, E., Perez-Cornago, A. ... Kaaks, R. (2021). Are circulating immune cells a determinant of pancreatic cancer risk? A prospective study using epigenetic cell count measures. Cancer Epidemiology, Biomarkers & Prevention, 30(12), 2179-2187. https://doi.org/10.1158/1055-9965.EPI-21-0169
