Environmental Exposure and Health

Humans are exposed to a plethora of environmental parameters all the time, all their lives. Examples include the quality of the air we breathe and the water we drink.

In the research group “Environmental Exposure and Health”, we explore how the environment affects our health. We model environmental exposures for the entire population, often with big data from monitoring programs and Geographical Information Systems (GIS), to estimate individuals’ lifetime exposures by linking our data with their residential history.

Using the nationwide renowned Danish health registers, we can carry out large epidemiological studies on the health effects of environmental exposures, including gene environment interactions. Examples of exposures include air pollution and nitrate in drinking water and their effects on health outcomes like NCDs, negative birth outcomes and infections.

Research areas

Our research projects cover the following topics, among others:

Air pollution and family related determinants of NCDs in the population
Nitrate in drinking water and risk of NCDs in the population
Nitrate in drinking water and risk of birth defects, and psychiatric diseases

Recent publications

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Chen, J., Rodopoulou, S., deHoogh, K., Strak, M., Andersen, Z. J., Atkinson, R., Bauwelinck, M., Bellander, T., Brandt, J., Cesaroni, G., Concin, H., Fecht, D., Forastiere, F., Gulliver, J., Hertel, O., Hoffmann, B., Hvidtfeldt, U. A., Janssen, N. A. H., Jöckel, K.-H. ... Hoek, G. (2021). Long-Term Exposure to Fine Particle Elemental Components and Natural and Cause-Specific Mortality—a Pooled Analysis of Eight European Cohorts within the ELAPSE Project. Environmental Health Perspectives, 129(4), Article 047009. https://doi.org/10.1289/EHP8368

Liu, S., Jørgensen, J. T., Ljungman, P., Pershagen, G., Bellander, T., Leander, K., Magnusson, P. K. E., Rizzuto, D., Hvidtfeldt, U. A., Raaschou-Nielsen, O., Wolf, K., Hoffmann, B., Brunekreef, B., Strak, M., Chen, J., Mehta, A., Atkinson, R. W., Bauwelinck, M., Varraso, R. ... Andersen, Z. J. (2021). Long-term exposure to low-level air pollution and incidence of asthma: the ELAPSE project. European Respiratory Journal. Supplement, 57(6), Article 2003099. https://doi.org/10.1183/13993003.030992020

Liu, S., Jørgensen, J. T., Ljungman, P., Pershagen, G., Bellander, T., Leander, K., Magnusson, P. K. E., Rizzuto, D., Hvidtfeldt, U. A., Raaschou-Nielsen, O., Wolf, K., Hoffmann, B., Brunekreef, B., Strak, M., Chen, J., Mehta, A., Atkinson, R. W., Bauwelinck, M., Varraso, R. ... Andersen, Z. J. (2021). Long-term exposure to low-level air pollution and incidence of chronic obstructive pulmonary disease: The ELAPSE project. Environment International, 146, Article 106267. https://doi.org/10.1016/j.envint.2020.106267

Strak, M., Weinmayr, G., Rodopoulou, S., Chen, J., de Hoogh, K., Andersen, Z. J., Atkinson, R., Bauwelinck, M., Bekkevold, T., Bellander, T., Boutron-Ruault, M.-C., Brandt, J., Cesaroni, G., Concin, H., Fecht, D., Forastiere, F., Gulliver, J., Hertel, O., Hoffmann, B. ... Samoli, E. (2021). Long term exposure to low level air pollution and mortality in eight European cohorts within the ELAPSE project: pooled analysis. BMJ (Clinical research ed.), 374, Article n1904. https://doi.org/10.1136/bmj.n1904

Wolf, K., Hoffmann, B., Andersen, Z. J., Atkinson, R. W., Bauwelinck, M., Bellander, T., Brandt, J., Brunekreef, B., Cesaroni, G., Chen, J., de Faire, U., de Hoogh, K., Fecht, D., Forastiere, F., Gulliver, J., Hertel, O., Hvidtfeldt, U. A., Janssen, N. A. H., Jørgensen, J. T. ... Ljungman, P. L. S. (2021). Long-term exposure to low-level ambient air pollution and incidence of stroke and coronary heart disease: a pooled analysis of six European cohorts within the ELAPSE project. The Lancet. Planetary Health, 5(9), e620-e632. https://doi.org/10.1016/S2542-5196(21)00195-9

Paudel, K., Adhikari, T. B. & Basel, P. (2021). Magnitude of sleep quality and factor associated among undergraduate medical students in Nepal: a cross-sectional study. Respirology, 26(S3), 407-407. Article P10-23. https://doi.org/10.1111/resp.14150_810

Sejbaek, C. S., Niclasen, J., Bonde, J. P. E., Kristensen, P., Larsen, A. D., Schlünssen, V. & Hougaard, K. S. (2021). Maternal exposure to psychosocial job strain during pregnancy and behavioral problems in the 11-year-old children: a Danish cohort study. European Child & Adolescent Psychiatry, 30(9), 1413-1426. https://doi.org/10.1007/s00787-020-01619-z

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