Diet, lifestyle and genetic susceptibility

Every day, each Dane consumes an average of 3 kilograms of food and fluids, which amounts to a ton each year. Food consumption habits have both health and environmental consequences. In the research group, we study associations between diet, lifestyle and health. The main outcomes we focus on are obesity, cardiovascular disease and cancer, both in one generation and across generations in families. Increasingly, we also study the interplay between food consumption, environmental impact, and health.

Research areas

  • Applying novel methods to assess associations between diet and health
  • Modelled substitution of foods
  • Socioeconomic determinants of food and drink habits
  • Associations between diet, lifestyle and obesity exposures in one generation, and health outcomes in the next
  • Environmentally sustainable foods or dietary habits and health
  • The interplay between genetic variation, diet, and health

Recent publications

Publications

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Ali, A. M. G., Schmidt, M. K., Bolla, M., Wang, Q., Gago-Dominguez, M., Esteban Castelao, J., Carracedo, A., Muñoz Garzón, V., Bojesen, S. E., Nordestgaard, B. G., Flyger, H., Chang-Claude, J., Vrieling, A., Rudolph, A., Seibold, P., Nevanlinna, H., Muranen, T. A., Aaltonen, K., Blomqvist, C. ... Pharoah, P. D. P. (2014). Alcohol Consumption and Survival after a Breast Cancer Diagnosis: A Literature-based Meta-analysis and Collaborative Analysis of Data for 29,239 Cases. Cancer Epidemiology, Biomarkers & Prevention, 23(6), 934-45. https://doi.org/10.1158/1055-9965.EPI-13-0901
Chan, S. S. M., Luben, R., Olsen, A., Tjonneland, A., Kaaks, R., Lindgren, S., Grip, O., Bergmann, M. M., Boeing, H., Hallmans, G., Karling, P., Overvad, K., Venø, S. K., van Schaik, F., Bueno-de-Mesquita, B., Oldenburg, B., Khaw, K.-T., Riboli, E. & Hart, A. R. (2014). Association between high dietary intake of the n-3 polyunsaturated fatty acid docosahexaenoic acid and reduced risk of Crohn's disease. Alimentary Pharmacology and Therapeutics, 39(8), 834-42. https://doi.org/10.1111/apt.12670
Chan, S. S. M., Luben, R., van Schaik, F., Oldenburg, B., Bueno-de-Mesquita, H. B., Hallmans, G., Karling, P., Lindgren, S., Grip, O., Key, T., Crowe, F. L., Bergmann, M. M., Overvad, K., Palli, D., Masala, G., Khaw, K.-T., Racine, A., Carbonnel, F., Boutron-Ruault, M.-C. ... Hart, A. R. (2014). Carbohydrate intake in the etiology of Crohn's disease and ulcerative colitis. Inflammatory Bowel Diseases, 20(11), 2013-21. https://doi.org/10.1097/MIB.0000000000000168
Muller, D. C., Fanidi, A., Midttun, Ø., Steffen, A., Dossus, L., Boutron-Ruault, M. C., Severi, G., Kühn, T., Katzke, V., De La Torre, R. A., González, C. A., Sánchez, M. J., Dorronsoro, M., Santiuste, C., Barricarte, A., Khaw, K. T., Wareham, N., Travis, R. C., Trichopoulou, A. ... Johansson, M. (2014). Circulating 25-hydroxyvitamin D3 in relation to renal cell carcinoma incidence and survival in the EPIC cohort. American Journal of Epidemiology, 180(8), 810-820. https://doi.org/10.1093/aje/kwu204
Tikk, K., Sookthai, D., Johnson, T., Rinaldi, S., Romieu, I., Tjønneland, A., Olsen, A., Overvad, K., Clavel-Chapelon, F., Baglietto, L., Boeing, H., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Palli, D., Pala, V., Tumino, R., Rosso, S., Panico, S. ... Kaaks, R. (2014). Circulating prolactin and breast cancer risk among pre- and postmenopausal women in the EPIC cohort. Annals of Oncology, 25(7). https://doi.org/10.1093/annonc/mdu150
Dik, V. K., Bueno-de-Mesquita, H. B., Van Oijen, M. G. H., Siersema, P. D., Uiterwaal, C. S. P. M., Van Gils, C. H., Van Duijnhoven, F. J. B., Cauchi, S., Yengo, L., Froguel, P., Overvad, K., Bech, B. H., Tjønneland, A., Olsen, A. V., Boutron-Ruault, M.-C., Racine, A., Fagherazzi, G., Kühn, T., Campa, D. ... Riboli, E. (2014). Coffee and tea consumption, genotype based CYP1A2 and NAT2 activity, and colorectal cancer risk - results from the EPIC cohort study. International Journal of Cancer, 135(2), 401-12. https://doi.org/10.1002/ijc.28655

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