Diet, lifestyle and genetic susceptibility

Every day, each Dane consumes an average of 3 kilograms of food and fluids, which amounts to a ton each year. Food consumption habits have both health and environmental consequences. In the research group, we study associations between diet, lifestyle and health. The main outcomes we focus on are obesity, cardiovascular disease and cancer, both in one generation and across generations in families. Increasingly, we also study the interplay between food consumption, environmental impact, and health.

Research areas

Applying novel methods to assess associations between diet and health
Modelled substitution of foods
Socioeconomic determinants of food and drink habits
Associations between diet, lifestyle and obesity exposures in one generation, and health outcomes in the next
Environmentally sustainable foods or dietary habits and health
The interplay between genetic variation, diet, and health

Recent publications

Publications

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van Duijnhoven, F. J. B., Jenab, M., Hveem, K., Siersema, P. D., Fedirko, V., Duell, E. J., Kampman, E., Halfweeg, A., van Kranen, H. J., van den Ouweland, J. M. W., Weiderpass, E., Murphy, N., Langhammer, A., Ness-Jensen, E., Olsen, A., Tjønneland, A., Overvad, K., Cadeau, C., Kvaskoff, M. ... Bueno-de-Mesquita, H. B. (2018). Circulating concentrations of vitamin D in relation to pancreatic cancer risk in European populations. International Journal of Cancer, 142(6), 1189-1201. https://doi.org/10.1002/ijc.31146

Kröger, J., Meidtner, K., Stefan, N., Guevara, M., Kerrison, N. D., Ardanaz, E., Aune, D., Boeing, H., Dorronsoro, M., Dow, C., Fagherazzi, G., Franks, P. W., Freisling, H., Gunter, M. J., Huerta, J. M., Kaaks, R., Key, T. J., Khaw, K. T., Krogh, V. ... Wareham, N. J. (2018). Circulating Fetuin-A and Risk of Type 2 Diabetes: A Mendelian Randomization Analysis. Diabetes, 67(6), 1200-1205. https://doi.org/10.2337/db17-1268

Andersen, V., Chan, S., Luben, R., Khaw, K.-T., Olsen, A., Tjonneland, A., Kaaks, R., Grip, O., Bergmann, M. M., Boeing, H., Hultdin, J., Karling, P., Overvad, K., Oldenburg, B., Opstelten, J., Boutron-Ruault, M.-C., Carbonnel, F., Racine, A., Key, T. ... Hart, A. (2018). Fibre intake and the development of inflammatory bowel disease: A European prospective multi-centre cohort study (EPIC-IBD). Journal of Crohn's & Colitis, 12(2), 129-136. Article jjx136. https://doi.org/10.1093/ecco-jcc/jjx136

Outzen, M., Tjønneland, A., Christensen, J. & Olsen, A. (2018). Fish consumption and prostate cancer risk and mortality in a Danish cohort study. European Journal of Cancer Prevention, 27(4), 355-360. https://doi.org/10.1097/CEJ.0000000000000330

Kopp, T. I., Outzen, M., Olsen, A., Vogel, U. & Ravn-Haren, G. (2018). Genetic polymorphism in selenoprotein P modifies the response to selenium-rich foods on blood levels of selenium and selenoprotein P in a randomized dietary intervention study in Danes. Genes and Nutrition, 13(1), Article 20. https://doi.org/10.1186/s12263-018-0608-4

Kyrø, C., Tjønneland, A., Overvad, K., Olsen, A. & Landberg, R. (2018). Higher Whole-Grain Intake Is Associated with Lower Risk of Type 2 Diabetes among Middle-Aged Men and Women: The Danish Diet, Cancer, and Health Cohort. The Journal of Nutrition, 148(9), 1434-1444. https://doi.org/10.1093/jn/nxy112

Li, S. X., Imamura, F., Schulze, M. B., Zheng, J., Ye, Z., Agudo, A., Ardanaz, E., Aune, D., Boeing, H., Dorronsoro, M., Dow, C., Fagherazzi, G., Grioni, S., Gunter, M. J., Huerta, J. M., Ibsen, D. B., Jakobsen, M. U., Kaaks, R., Key, T. J. ... Wareham, N. J. (2018). Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: Analysis within EPIC-InterAct across eight European countries. Diabetologia, 61(6), 1325-1332. https://doi.org/10.1007/s00125-018-4586-2

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Revised 22.01.2026

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