Epidemiology

The Research Unit for Epidemiology develops and delivers teaching and research in human epidemiology. Our research includes epidemiological themes such as diet, lifestyle, reproduction, vaccines, environment, genetics and medication. And we find common ground in the application of epidemiological methods to address health challenges.

We work with a wide set of national and international collaborators at leading research centres, and our vision is to develop into one of the global centres of research excellence in epidemiology by developing a portfolio of research projects that apply state-of-the-art epidemiological methods to resolve societally and academically important research questions.

The research unit’s research covers different epidemiological aims, such as:

  • descriptive epidemiology of trends in the occurrence of conditions and diseases, their risk factors and complications based on Danish and international register data,
  • aetiological observational epidemiology examining the contribution of a wide variety of physiological, behavioural, societal and genetic mechanisms to the risk of health outcomes, including diseases and their complications, using both Danish and international cohorts and
  • data collection, processing and/or analysis of several core Danish cohorts and trials.

Methods

Epidemiological methods focus on the quantitative analysis of occurrence of health outcomes and their determinants at the level of populations. Epidemiological methods include study designs (sampling, data collection and processing, quality control), and statistical analytical approaches combined with subject matter knowledge.

The aim is to chart the distribution of health conditions and to determine causes of population health. Although different groups of researchers within the unit focus on different exposures and different health outcomes, the strength of the research unit lies in a shared focus on applying rigorous epidemiologic principles and methodological approaches and in the group’s ability to define, develop and apply the most appropriate scientific strategy to explore a given research question.

Recent publications

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Rosson, G. D., Dellon, A. L., Gross, R., Sone, H., Mizuno, S., Yamada, N., Tesfaye, S., Witte, D. R. & Fuller, J. H. (2005). Vascular risk factors and diabetic neuropathy. The New England Journal of Medicine, 352(18), 1925-1927. https://doi.org/10.1056/NEJM200505053521817
Jeurnink, S., Büchner, F., Bueno-de-Mesquita, H., Siersema, P., Boshuizen, H., Numans, M., Dahm, C. C., Overvad, K., Tjønneland, A., Roswall, N., Clavel-Chapelon, F., Boutron-Ruault, M., Morois, S., Kaaks, R., Teucher, B., Boeing, H., Buijsse, B., Trichopoulou, A., Benetou, V. ... Gonzalez, C. (2012). Variety in vegetable and fruit consumption and the risk of gastric and esophageal cancer in the European Prospective investigation into cancer and nutrition (EPIC). International Journal of Cancer, 131(6), E963-73. https://doi.org/10.1002/ijc.27517
Büchner, F. L., Bueno-de-Mesquita, H. B., Ros, M. M., Overvad, K., Dahm, C. C., Hansen, L., Tjønneland, A., Clavel-Chapelon, F., Boutron-Ruault, M.-C., Touillaud, M., Kaaks, R., Rohrmann, S., Boeing, H., Nöthlings, U., Trichopoulou, A., Zylis, D., Dilis, V., Palli, D., Sieri, S. ... Riboli, E. (2010). Variety in Fruit and Vegetable Consumption and the Risk of Lung Cancer in the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiology, Biomarkers & Prevention, 19(9), 2278-86. https://doi.org/10.1158/1055-9965.EPI-10-0489
Peeters, P. H., Slimani, N., van der Schouw, Y. T., Grace, P. B., Navarro, C., Tjønneland, A., Olsen, A. V., Clavel-Chapelon, F., Touillaud, M., Boutron-Ruault, M. C., Jenab, M., Kaaks, R., Linseisen, J., Trichopoulou, A., Trichopoulos, D., Dilis, V., Boeing, H., Weikert, C., Overvad, K. ... Bingham, S. A. (2007). Variations in plasma phytoestrogen concentrations in European adults. Journal of Nutrition, 137(5), 1294-300.
Campa, D., Claus, R., Dostal, L., Stein, A., Chang-Claude, J., Meidtner, K., Boeing, H., Olsen, A., Tjønneland, A., Overvad, K., Rodríguez, L., Bonet, C., Sánchez, M.-J., Amiano, P., Huerta, J. M., Barricarte, A., Khaw, K.-T., Wareham, N., Travis, R. C. ... Kaaks, R. (2011). Variation in genes coding for AMP-activated protein kinase (AMPK) and breast cancer risk in the European Prospective Investigation on Cancer (EPIC). Breast Cancer Research and Treatment, 127(3), 761-767. https://doi.org/10.1007/s10549-010-1269-1
Dideriksen, M., Soegaard, C. & Nielsen, R. O. (2016). Validity of self-reported running distance. Journal of Strength and Conditioning Research, 30(6), 1592-1596. https://doi.org/10.1519/JSC.0000000000001244

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